In a match that has been widely talked about since the draws took place, Chelsea would welcome an in-form Barcelona team to the Stamford Bridge.
The occasion is the first leg of the Uefa Champions League round of 16 on Tuesday night and the stage is set as both teams resume hostilities.
The Blues were in FA Cup action on Friday and had no trouble against Hull City in the fifth round, with a 4-0 victory which sent them into the quarter finals.
Barcelona, on the other hand, saw off Eibar 2-0 on Saturday to maintain their lead seven point lead atop the Primera Division standings.
Video | Lionel Messi vs. Chelsea (2006 CL). The day Leo Messi truly announced himself to the world. At 18, with so many big names he tore Mourinho’s record breaking Chelsea side to shreds.pic.twitter.com/JjWfMiVydV
— FC Barcelona (@BarcaUniversal) February 20, 2018
Barcelona travel with their full squad – excluding Philipe Coutinho, who is cup-tied after appearing for Liverpool in the competition earlier this season.
The Blaugrana can count on big money signing, Ousmane Dembele as he is available for selection after suffering an injury earlier in the month.
Barcelona are expected to start with Marc Ter Stegen in goal while the trio of Pique, Umtiti and Alba are expected to be joined by Sergi Roberto.
You can of course expect Lionel Messi, Luis Suarez and Andres Iniesta to feature from the start for the Spanish team.
Chelsea can also boast of enough attacking firepower with Eden Hazard the man to watch for the blues. Alvaro Morata would be fighting for a place upfront as he faces competition from Olivier Giroud.
Cesc Fabregas would also hope to start against his former club and would likely be partnered alongside Ngolo Kante.
The backline would be a source of concern for Chelsea but it would likely be the usual suspects with Courtois in goal, Azpilicueta, Cahill, Marco Alonso and Victor Moses.
This will be the 13th time that these two giants will face each other, making it the fifth most played fixture in the Champions League.
Chelsea are unbeaten in their last seven European meetings (two wins, five draws) with the Catalans and are good to avoid defeat at (1.70).
Lionel Messi has played 655 minutes against Chelsea in the Champions League but is yet to score. This makes Conte’s men the team he has featured for that many minutes and not net.